Publications

Hematopoietic Stem Cell Transplantation Using Single UM171-expanded Cord Blood: A Single-Arm, Phase 1-2 Safety and Feasibility Study
Cohen, S., Roy, J., Lachance, S., Delisle, J.S., Marinier, A., Busque, L., Roy, D.C., Barabé, F., Ahmad, I., Bambace, N., Bernard, L., Kiss, T., Philippe Bouchard, P., Caudrelier, P. Landais, S., Larochelle, F., Chagraoui, J., Lehnertz, B., Corneau, S., Tomellini, E., van Kampen J.J.A., Cornelissen, J.J., Dumont-Lagacé, M., Tanguay, M., Li, Q., Lemieux, S., Zandstra, P.W., Sauvageau, G.
The Lancet Haematology. 2020 Feb 1;7(2):e134-45. doi: 10.1016/S2352-3026(19)30202-9
PMID: 31704264

UM171 enhances lentiviral gene transfer and recovery of primitive human hematopoietic cells
Ngom, M., Imren, S., Maetzig, T., Adair, J. E., Knapp, D. J., Chagraoui, J., Fares, I., Bordeleau, M., Sauvageau, G., Leboulch, P., Eaves, C., Humphries, R. K.
Mol Ther Methods Clin Dev. 2018 Sep 21; 10: 156–164.
PMCID: PMC6077133

EPCR expression marks UM171-expanded CD34+ cord blood stem cells
Fares, I., Chagraoui, J., Lehnertz, B., MacRae, T., Mayotte, N., Tomellini, E., Aubert, L., Roux, P. P., Sauvageau, G.
Blood. 2017 Jun 22;129(25):3344-3351. doi: 10.1182/blood-2016-11-750729. Epub 2017 Apr 13.
PMID: 28408459

Small molecule regulation of normal and leukemic stem cells
Fares, I., Rivest-Khan, L., Cohen, S., Sauvageau, G.
Curr Opin Hematol. 2015 Jul;22(4):309-16. doi: 10.1097/ MOH.0000000000000151. Review.
PMID: 26049751

Pyrimidole derivatives are agonists of human hematopoietic stem cell self-renewal
Fares, I., Chagraoui, J., Gareau, Y., Gingras, S., Ruel, R., Mayotte, N., Csaszar, E., Knapp, D. J., Miller, P., Ngom, M., Imren, S., Roy, D. C., Watts, K. L., Kiem, H. P., Herrington, R., Iscove, N. N., Humphries, R. K., Eaves, C. J., Cohen, S., Marinier, A., Zandstra, P. W., Sauvageau, G.
Science. 2014 Sep 19;345(6203):1509-12. doi: 10.1126/science.1256337.
PMID: 25237102

Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling
Csaszar, E., Kirouac, D. C., Yu, M., Wang, W., Qiao, W., Cooke, M. P., Boitano, A. E., Ito, C., Zandstra, P. W.
Cell Stem Cell. 2012 Feb 3;10(2):218-29. doi: 10.1016/j.stem.2012.01.003.
PMID: 22305571

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