Publications

Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling
Csaszar, E., Kirouac, D. C., Yu, M., Wang, W., Qiao, W., Cooke, M. P., Boitano, A. E., Ito, C., Zandstra, P. W.
Cell Stem Cell. 2012 Feb 3;10(2):218-29. doi: 10.1016/j.stem.2012.01.003.
PMID: 22305571

Pyrimidole derivatives are agonists of human hematopoietic stem cell self-renewal
Fares, I., Chagraoui, J., Gareau, Y., Gingras, S., Ruel, R., Mayotte, N., Csaszar, E., Knapp, D. J., Miller, P., Ngom, M., Imren, S., Roy, D. C., Watts, K. L., Kiem, H. P., Herrington, R., Iscove, N. N., Humphries, R. K., Eaves, C. J., Cohen, S., Marinier, A., Zandstra, P. W., Sauvageau, G.
Science. 2014 Sep 19;345(6203):1509-12. doi: 10.1126/science.1256337.
PMID: 25237102

Small molecule regulation of normal and leukemic stem cells
Fares, I., Rivest-Khan, L., Cohen, S., Sauvageau, G.
Curr Opin Hematol. 2015 Jul;22(4):309-16. doi: 10.1097/ MOH.0000000000000151. Review.
PMID: 26049751

EPCR expression marks UM171-expanded CD34+ cord blood stem cells
Fares, I., Chagraoui, J., Lehnertz, B., MacRae, T., Mayotte, N., Tomellini, E., Aubert, L., Roux, P. P., Sauvageau, G.
Blood. 2017 Jun 22;129(25):3344-3351. doi: 10.1182/blood-2016-11-750729. Epub 2017 Apr 13.
PMID: 28408459

UM171 enhances lentiviral gene transfer and recovery of primitive human hematopoietic cells
Ngom, M., Imren, S., Maetzig, T., Adair, J. E., Knapp, D. J., Chagraoui, J., Fares, I., Bordeleau, M., Sauvageau, G., Leboulch, P., Eaves, C., Humphries, R. K.
Mol Ther Methods Clin Dev. 2018 Sep 21; 10: 156–164.
PMCID: PMC6077133